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. Author manuscript; available in PMC: 2019 Feb 15.
Published in final edited form as: Cell Signal. 2018 Apr 17;47:142–150. doi: 10.1016/j.cellsig.2018.04.004

Fig. 3.

Fig. 3.

Effects of RANKL and TRAIL on NF-κB activation in a HAEC:HASMC transwell co-culture model. HAECs were treated for 72 h with RANKL (0–25 ng/ml), TRAIL (0–25ng/ml), or a combination of both ligands (see key below). HASMCs were then harvested and monitored by Western blotting for activation of NF-κB as follows: (A) p52/p100 ratio; and (B) Phospho-p65/p65 ratio. Histograms represent fold change in band intensity relative to untreated controls. Blots are representative. Key: 5R, 5 ng/ml RANKL; 25R, 25 ng/ml RANKL; 5T, 5 ng/ml TRAIL.