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The atypical features of the ALDH16 family. (A) Domain diagram of ALDH16. ALDH16 is unique in the ALDH superfamily in having an extra domain near the C-terminus. Abbreviation: ALDHSF, aldehyde dehydrogenase superfamily. (B) ALDH16 phylogenetic tree and an alignment of the catalytic loops of several ALDH16s. Note the absence of the predicted catalytic Cys in some ALDH16 proteins.
