Table 3. Univariate analysis of the association between clinical variables and disability grade upon release from multidrug treatment (MDT) in new cases of leprosy reported at Eduardo de Menezes Hospital, 2005-2010.
| Grade 0 | Grade 1 | Grade 2 | p-value | |
|---|---|---|---|---|
| Skin lesion count (n=250) | ||||
| 1 | 55 (90.2%) | 3 (4.9%) | 3 (4.9%) | <0.001* |
| 2 to 5 | 34 (75.6%) | 6 (13.3%) | 5 (11.1%) | |
| ≥ 6 | 78 (54.2%) | 30 (20.8%) | 36 (25.0%) | |
| Nerve enlargement (n=255) | ||||
| No | 145 (78.0%) | 25 (13.4%) | 16 (8.6%) | <0.001* |
| Yes | 23 (33.3%) | 16 (23.2%) | 30 (43.5%) | |
| Sensory impairment (n=255) | ||||
| No | 142 (91.6%) | 11 (7.1%) | 2 (1.3%) | <0.001* |
| Yes | 26 (26.0%) | 30 (30.0%) | 44 (44.0%) | |
| Motor impairment (n=255) | ||||
| No | 160 (78.8%) | 30 (14.8%) | 13 (6.4%) | <0.000* |
| Yes | 8 (15.4%) | 11 (21.2%) | 33 (63.5%) | |
| Madrid classification (n=255) | ||||
| Indeterminate | 20 (100%) | 0 (0.0%) | 0 (0.0%) | <0.001** |
| Tuberculoid | 38 (90.4%) | 2 (4.8%) | 2 (4.8%) | |
| Borderline | 82 (58.6%) | 29 (20.7%) | 29 (20.7%) | |
| Lepromatous | 28 (52.8%) | 10 (18.9%) | 15 (28.3%) | |
| Operational classification (n=255) | ||||
| Paucibacillary | 79 (84.9%) | 7 (7.5%) | 7 (7.5%) | <0.001* |
| Multibacillary | 89 (54.9%) | 34 (21.0%) | 39 (24.1%) | |
| Leprosy reactions (n=255) | ||||
| None | 114 (86.4%) | 9 (6.8%) | 9 (6.8%) | <0.001** |
| Neuritis only | 17 (35.4%) | 11 (22.9%) | 20 (41.7%) | |
| Type 1 and 2 | 2 (33.3%) | 1 (16.7%) | 3 (50.0%) | |
| Type 1 | 15 (53.6%) | 10 (35.7%) | 3 (10.7%) | |
| Type 2 | 20 (48.8%) | 10 (24.4%) | 11 (26.8%) | |
| Treatment (n=255) | ||||
| Standard MDT regimen | 140 (66.4%) | 36 (17.1%) | 35 (16.6%) | 0.332* |
| Alternative MDT regimen | 28 (63.6%) | 5 (11.4%) | 11 (25.0%) |
Note: * Chi-square test ** Fisher exact test; n= number of cases