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. 2019 Feb 12;7:e6356. doi: 10.7717/peerj.6356

Table 1. Estimated difference in incidence (% and 95% CI) of alcohol drinking and tobacco cigarette smoking across different time periods based on the National Minimum Drinking Age Act and the Synar Amendment.

Age Period 3 vs. Period 2 Period 3 vs. Period 1 Period 2 vs. Period 1 Period 3 vs. Period 0 Period 2 vs. Period 0 Period 1 vs. Period 0
Alcohol
12 −3.6 (−5.2,−2.0) −3.9 (−5.8,−1.9) −0.3 (−2.2,1.7) −15.9 (−20.9,−10.9) −12.3 (−17.3,−7.3) −12.1 (−17.2,−6.9)
13 −4.7 (−6.3,−3.1) −5.5 (−7.6,−3.4) −0.8 (−2.9,1.4) −19.2 (−23.5,−14.8) −14.4 (−18.8,−10.1) −13.7 (−18.3,−9.1)
14 −5.0 (−7.3,−2.7) −4.3 (−7.0,−1.5) 0.7 (−2.0,3.5) −14.1 (−19.9,−8.4) −9.1 (−14.8,−3.4) −9.9 (−15.8,−3.9)
15 −4.4 (−6.5,−2.3) −2.1 (−4.9,0.7) 2.3 (−0.5,5.1) −22.6 (−28.8,−16.3) −18.1 (−24.4,−11.9) −20.5 (−27.0,−13.9)
16 −2.4 (−4.2,−0.6) −3.4 (−6.0,−0.9) −1.0 (−3.6,1.6) −17.9 (−24.0,−11.9) −15.5 (−21.5,−9.5) −14.5 (−20.8,−8.2)
17 −2.6 (−4.5,−0.6) −1.3 (−4.6,2.0) 1.3 (−2.1,4.6) −18.3 (−26.0,−10.5) −15.7 (−23.5,−8.0) −17.0 (−25.2,−8.8)
18 1.1 (−1.7,3.9) 4.7 (0.1,9.3) 3.6 (−1.0,8.2) −14.7 (−25.6,−3.7) −15.8 (−26.8,−4.9) −19.4 (−30.9,−7.9)
19 −2.0 (−4.7,0.6) 2.1 (−2.3,6.4) 4.1 (−0.3,8.5) −22.6 (−32.6,−12.6) −20.6 (−30.6,−10.6) −24.7 (−35.3,−14.1)
20 0.4 (−2.6,3.4) 6.4 (1.9,10.9) 6.0 (1.4,10.6) −12.4 (−26.0,1.2) −12.8 (−26.4,0.8) −18.8 (−32.8,−4.8)
21 13.1 (8.4,17.8) 27.3 (20.4,34.2) 14.2 (7.2,21.1) 29.4 (16.1,42.7) 16.3 (2.9,29.7) 2.1 (−12.2,16.4)
22–23 1.8 (0.6,2.9) 3.8 (2.3,5.2) 2.0 (0.6,3.4) −0.4 (−5.7,5.0) −2.1 (−7.5,3.2) −4.1 (−9.6,1.3)
Tobacco
12 −3.1 (−4.3,−1.9) −8.0 (−9.5,−6.4) −4.8 (−6.4,−3.3) −8.1 (−10.0,−6.1) −4.9 (−6.9,−3.0) −0.1 (−2.3,2.1)
13 −3.9 (−6.3,−1.6) −9.6 (−12.2,−7.0) −5.7 (−8.1,−3.2) −8.2 (−11.2,−5.3) −4.3 (−7.1,−1.4) 1.4 (−1.7,4.5)
14 −4.1 (−6.5,−1.7) −9.5 (−12.2,−6.7) −5.4 (−8.0,−2.8) −5.1 (−8.1,−2.1) −1.0 (−3.9,1.9) 4.4 (1.2,7.5)
15 −3.7 (−5.9,−1.5) −7.7 (−10.3,−5.1) −4.0 (−6.5,−1.5) −3.5 (−6.5,−0.4) 0.2 (−2.7,3.1) 4.2 (1.0,7.5)
16 −3.3 (−4.8,−1.8) −6.3 (−8.4,−4.3) −3.0 (−5.0,−1.0) −0.7 (−3.0,1.6) 2.6 (0.3,4.8) 5.6 (3.0,8.2)
17 −0.9 (−2.6,0.8) −4.5 (−6.9,−2.2) −3.6 (−5.9,−1.3) 1.8 (−1.1,4.8) 2.7 (−0.2,5.7) 6.3 (3.0,9.7)
18 2.4 (−0.4,5.1) 3.8 (0.5,7.1) 1.4 (−1.7,4.5) 12.0 (8.5,15.4) 9.6 (6.3,12.9) 8.2 (4.4,11.9)
19 1.8 (>−0.1,3.6) 1.3 (−1.2,3.8) −0.5 (−2.9,1.9) 5.1 (2.0,8.1) 3.3 (0.3,6.2) 3.8 (0.3,7.2)
20 1.6 (0.1,3.2) 1.1 (−1.0,3.1) −0.6 (−2.4,1.3) 4.1 (1.6,6.6) 2.4 (0.0,4.8) 3.0 (0.3,5.7)
21 −0.1 (−1.7,1.5) −0.7 (−2.9,1.5) −0.6 (−2.7,1.4) 4.5 (2.3,6.7) 4.6 (2.5,6.7) 5.2 (2.7,7.8)
22–23 0.2 (−0.2,0.7) 0.6 (0.1,1.1) 0.3 (−0.2,0.8) 1.4 (0.8,1.9) 1.1 (0.6,1.6) 0.8 (0.2,1.3)

Notes:

Data from NSDUH, 1979–2015.

For alcohol drinking, Period 0 = 1979–1986, Period 1 = 1987–1996, Period 2 = 1997–2006, Period 3 = 2007–2015; for tobacco smoking, Period 0 = 1979–1992, Period 1 = 1993–1999, Period 2 = 2000–2007, Period 3 = 2008–2015. Bold font indicates statistical significance at 0.05 level.