Table 6. Schizotypal Personality Questionnaire (SPQ) scores in our sample of female carriers of genetic mutations associated with X-linked ichthyosis (XLI) and a normative general population control sample.

	Female carriers for XLI-associated mutations (n = 88)	Normative adult female sample (n = 184, [37])	Statistical comparison
Total score	24.0 (95%CI: 20.0–28.5); 25.5±15.2	15.9±11.4	t[135] = 5.27, p<0.0001
Ideas of reference	2.4±2.5	1.71±2.06	t[146] = 2.33, p = 0.02
Excessive social anxiety	4.0 (95%CI: 3.0–6.0); 4.4±2.8	3.04±2.39	t[150] = 3.88, p<0.0005
Odd beliefs or magical thinking	1.0 (95%CI: 0.0–1.0); 1.5±1.7	2.08±1.81	t[179] = -2.76, p = 0.0064
Unusual perceptual experiences	2.0 (95%CI: 1.0–2.0); 2.1±2.0	1.91±2.10	t[182] = 0.65, p = 0.52
Odd or eccentric behaviour	1.0 (95%CI: 0.5–2.0); 2.0±2.1	0.75±1.43	t[126] = 5.05, p<0.0001
No close friends	3.0 (95%CI: 2.0–5.5); 3.9±3.0	1.49±1.84	t[120] = 6.93, p<0.0001
Odd speech	4.0 (95%CI: 3.0–5.0); 3.8±2.6	2.40±2.13	t[144] = 4.32, p<0.0001
Constricted affect	2.0 (95%CI: 2.0–3.0); 2.7±2.3	1.05±1.28	t[114] = 6.37, p<0.0001
Suspiciousness	2.0 (95%CI: 2.0–3.0); 2.9±2.5	1.51±1.80	t[132] = 4.56, p<0.0001