Table 8. Demographics of our sample of female carriers of genetic mutations associated with X-linked ichthyosis (XLI) and our adult female general population sample of mothers.
| Demographic variable | Female carrier mothers for XLI-associated mutations (n = 83) | General UK and USA population sample of mothers (n = 263) | Statistical comparison |
|---|---|---|---|
| Age (yrs) | 39.0 (95%CI: 37.0–42.0) | 37.0 (95%CI: 35.0–38.0) | U = 8287.5, p = 0.001 |
| Age at first child (yrs) | 27.4±5.4 | 25.0 (95%CI: 24.0–26.0); 25.5±5.7 | U = 6650.5, p = 0.005 |
| Number of children | 2.0 (95%CI: 2.0–2.0) | 2.0 (95%CI: 2.0–2.0) | U = 9138.0, p = 0.04 |
|
Handedness (Right/Left or Mixed) |
75(90%)/8(10%) | 233(89%)/30(11%) | χ2[1] = 0.06, p = 0.81 |
|
Ethnicity (White European or Hispanic/Other) |
75(90%)/8(10%) | 237(90%)/26(10%) | χ2[1] = 0.02, p = 0.89 |
|
Highest level of education (No formal or high school/college or University/postgraduate) |
22(27%)/45(54%)/16(19%) | 75(29%)/154(59%)/33(12%) (1 no response) |
χ2[2] = 2.31, p = 0.32 |
|
Smoking status (Regular smoker/Non-smoker) |
30(36%)/53(63%) | 123(47%)/140(53%) | χ2[1] = 2.47, p = 0.12 |