Table 1. Univariable analysis of relapse cases >16 years of age, London, 2009–2015.
| Exposure | Relapse TB cases | Non-relapse TB cases | Odds Ratio | 95% confidence interval | p* | |||||
|---|---|---|---|---|---|---|---|---|---|---|
| Total | Exposed | % | Total | Exposed | % | |||||
| Sex | Male | 298 | 164 | 55 | 19,802 | 11,637 | 58.8 | 0.86 | [0.68–1.09] | 0.194 |
| Social risk factors | Any risk factors | 256 | 38 | 14.8 | 17,539 | 1,826 | 10.4 | 1.5 | [1.03–2.13] | 0.021 |
| Homelessness | 283 | 21 | 7.42 | 18,787 | 642 | 3.42 | 2.27 | [1.37–3.57] | <0.001 | |
| Prison history | 278 | 14 | 5.04 | 18,737 | 478 | 2.55 | 2.03 | [1.08–3.49] | 0.01 | |
| Drug use | 277 | 16 | 5.78 | 18,697 | 690 | 3.69 | 1.6 | [0.90–2.67] | 0.069 | |
| Alcohol use | 258 | 14 | 5.43 | 17,731 | 782 | 4.41 | 1.24 | [0.67–2.14] | 0.431 | |
| Site of infection | CNS* TB | 298 | 50 | 16.8 | 19,805 | 2,312 | 11.7 | 1.53 | [1.10–2.08] | 0.007 |
| Time since entry into UK | UK born | 271 | 33 | 12.2 | 17,415 | 2,770 | 15.9 | Reference | ||
| 0–1 years | 271 | 58 | 21.4 | 17,415 | 2,562 | 14.7 | 1.9 | [1.24–2.92] | 0.003 | |
| 2–5 years | 271 | 77 | 28.4 | 17,415 | 4,138 | 23.8 | 1.56 | [1.04–2.36] | 0.033 | |
| 6–10 years | 271 | 42 | 15.5 | 17,415 | 2,864 | 16.5 | 1.23 | [0.78–1.95] | 0.375 | |
| 11+ years | 271 | 61 | 22.5 | 17,415 | 5,081 | 29.2 | 1.01 | [0.66–1.54] | 0.972 | |
| Ethnic group | Indian | 295 | 94 | 31.9 | 19,625 | 5,870 | 29.9 | Reference | ||
| White | 295 | 34 | 11.5 | 19,625 | 2,171 | 11.1 | 0.98 | [0.66–1.45] | 0.912 | |
| Black Caribbean | 295 | 4 | 1.36 | 19,625 | 655 | 3.34 | 0.38 | [0.14–1.04] | 0.06 | |
| Black African | 295 | 62 | 21 | 19,625 | 4,331 | 22.1 | 0.89 | [0.65–1.23] | 0.496 | |
| Pakistani | 295 | 25 | 8.47 | 19,625 | 1,963 | 10 | 0.8 | [0.51–1.24] | 0.312 | |
| Bangladeshi | 295 | 19 | 6.44 | 19,625 | 1,152 | 5.87 | 1.03 | [0.63–1.69] | 0.907 | |
| Mixed/other | 295 | 57 | 19.3 | 19,625 | 3,483 | 17.8 | 1.02 | [0.73–1.42] | 0.898 | |
| World region of birth | West Europe | 283 | 39 | 13.8 | 19,054 | 3,231 | 17 | Reference | ||
| Central Europe | 283 | 15 | 5.3 | 19,054 | 599 | 3.14 | 2.07 | [1.14–3.79] | 0.017 | |
| East Asia | 283 | 3 | 1.06 | 19,054 | 198 | 1.04 | 1.26 | [0.38–4.10] | 0.706 | |
| East Europe | 283 | 4 | 1.41 | 19,054 | 158 | 0.83 | 2.1 | [0.74–5.94] | 0.163 | |
| East Mediterranean | 283 | 1 | 0.35 | 19,054 | 160 | 0.84 | 0.52 | [0.07–3.79] | 0.517 | |
| North Africa | 283 | 4 | 1.41 | 19,054 | 194 | 1.02 | 1.71 | [0.60–4.83] | 0.313 | |
| North America & Oceania | 283 | 1 | 0.35 | 19,054 | 41 | 0.22 | 2.02 | [0.27–15.1] | 0.492 | |
| South Asia | 283 | 142 | 50.2 | 19,054 | 8,975 | 47.1 | 1.31 | [0.92–1.87] | 0.137 | |
| South East Asia | 283 | 5 | 1.77 | 19,054 | 634 | 3.33 | 0.65 | [0.26–1.66] | 0.372 | |
| South, Central America & the Caribbean | 283 | 5 | 1.77 | 19,054 | 430 | 2.26 | 0.96 | [0.38–2.46] | 0.938 | |
| Sub-Saharan Africa | 283 | 64 | 22.6 | 19,054 | 4,291 | 22.5 | 1.24 | [0.83–1.84] | 0.301 | |
| Unknown | 283 | 0 | 0 | 19,054 | 143 | 0.75 | ||||
| Age group | 16–19 | 298 | 12 | 4.03 | 19,805 | 844 | 4.26 | Reference | ||
| 20–29 | 298 | 106 | 35.6 | 19,805 | 5,750 | 29 | 1.3 | [0.71–2.37] | 0.397 | |
| 30–39 | 298 | 92 | 30.9 | 19,805 | 5,195 | 26.2 | 1.25 | [0.68–2.28] | 0.478 | |
| 40–49 | 298 | 39 | 13.1 | 19,805 | 3,179 | 16.1 | 0.86 | [0.45–1.66] | 0.657 | |
| 50–59 | 298 | 23 | 7.72 | 19,805 | 2,062 | 10.4 | 0.78 | [0.39–1.58] | 0.5 | |
| 60–69 | 298 | 17 | 5.7 | 19,805 | 1,335 | 6.74 | 0.9 | [0.43–1.88] | 0.77 | |
| 70–79 | 298 | 8 | 2.68 | 19,805 | 983 | 4.96 | 0.57 | [0.23–1.41] | 0.22 | |
| 80+ | 298 | 1 | 0.34 | 19,805 | 457 | 2.31 | 0.15 | [0.02–1.19] | 0.07 | |
*From Wald test.