Table 3. Univariable analysis of reinfection cases >16 years of age, London, 2009–2015.
Exposure | Reinfection TB cases | Non- Reinfection TB cases | Odds Ratio | 95% confidence interval | p* | |||||
---|---|---|---|---|---|---|---|---|---|---|
Total | Exposed | % | Total | Exposed | % | |||||
Sex | Male | 880 | 492 | 55.91 | 19,220 | 11,309 | 58.84 | 0.89 | [0.77–1.02] | 0.084 |
Social risk factors | Any risk factors | 766 | 125 | 16.32 | 17,029 | 1,739 | 10.21 | 1.71 | [1.40–2.10] | <0.001 |
Homelessness | 841 | 46 | 5.47 | 18,229 | 617 | 3.38 | 1.65 | [1.19–2.25] | 0.001 | |
Prison history | 836 | 40 | 4.78 | 18,179 | 452 | 2.49 | 1.97 | [1.38–2.75] | <0.001 | |
Drug use | 834 | 45 | 5.4 | 18,140 | 661 | 3.64 | 1.51 | [1.08–2.06] | 0.009 | |
Alcohol use | 776 | 54 | 6.96 | 17,213 | 742 | 4.31 | 1.66 | [1.22–2.21] | <0.001 | |
Site of disease | CNS* TB | 880 | 104 | 11.82 | 19,223 | 2,258 | 11.75 | 1.01 | [0.81–1.24] | 0.948 |
Time since entry into UK | UK born | 803 | 111 | 13.82 | 16,883 | 2,692 | 15.95 | Reference | ||
0–1 years | 803 | 69 | 8.59 | 16,883 | 2,551 | 15.11 | 0.66 | [0.48–0.89] | 0.007 | |
2–5 years | 803 | 110 | 13.7 | 16,883 | 4,105 | 24.31 | 0.65 | [0.50–0.85] | 0.002 | |
6–10 years | 803 | 157 | 19.55 | 16,883 | 2,749 | 16.28 | 1.39 | [1.08–1.78] | 0.01 | |
11+ years | 803 | 356 | 44.33 | 16,883 | 4,786 | 28.35 | 1.80 | [1.45–2.24] | <0.001 | |
Ethnic group | Indian | 879 | 230 | 26.17 | 19,041 | 5,734 | 30.11 | Reference | ||
White | 879 | 108 | 12.29 | 19,041 | 2,097 | 11.01 | 1.28 | [1.02–1.62] | <0.001 | |
Black Caribbean | 879 | 19 | 2.16 | 19,041 | 640 | 3.36 | 0.74 | [0.46–1.19] | 0.214 | |
Black African | 879 | 233 | 26.51 | 19,041 | 4,160 | 21.85 | 1.40 | [1.16–1.68] | <0.001 | |
Pakistani | 879 | 89 | 10.13 | 19,041 | 1,899 | 9.97 | 1.17 | [0.91–1.50] | 0.223 | |
Bangladeshi | 879 | 41 | 4.66 | 19,041 | 1,130 | 5.93 | 0.90 | [0.64–1.27] | 0.561 | |
Mixed/other | 879 | 159 | 18.09 | 19,041 | 3,381 | 17.76 | 1.17 | [0.95–1.44] | 0.131 | |
World region of birth | West Europe | 841 | 130 | 15.46 | 18,496 | 3,140 | 16.98 | Reference | ||
Central Europe | 841 | 28 | 3.33 | 18,496 | 586 | 3.17 | 1.15 | [0.76–1.75] | 0.501 | |
East Asia | 841 | 8 | 0.95 | 18,496 | 193 | 1.04 | 1.00 | [0.48–2.07] | 0.997 | |
East Europe | 841 | 9 | 1.07 | 18,496 | 153 | 0.83 | 1.42 | [0.71–2.85] | 0.322 | |
East Mediterranean | 841 | 8 | 0.95 | 18,496 | 153 | 0.83 | 1.26 | [0.61–2.63] | 0.532 | |
North Africa | 841 | 14 | 1.66 | 18,496 | 184 | 0.99 | 1.84 | [1.04–3.25] | 0.037 | |
North America & Oceania | 841 | 0 | 0 | 18,496 | 42 | 0.23 | 1.00 | |||
South Asia | 841 | 348 | 41.38 | 18,496 | 8,769 | 47.41 | 0.96 | [0.78–1.18] | 0.686 | |
South East Asia | 841 | 36 | 4.28 | 18,496 | 603 | 3.26 | 1.44 | [0.99–2.11] | 0.059 | |
South, Central America & Caribbean | 841 | 12 | 1.43 | 18,496 | 423 | 2.29 | 0.69 | [0.38–1.25] | 0.217 | |
Sub-Saharan Africa | 841 | 245 | 29.13 | 18,496 | 4,110 | 22.22 | 1.44 | [1.16–1.79] | 0.001 | |
Unknown | 841 | 3 | 0.36 | 18,496 | 140 | 0.76 | 0.52 | [0.16–1.65] | 0.265 | |
Age group | 16–19 | 880 | 16 | 1.82 | 19,223 | 840 | 4.37 | Reference | ||
20–29 | 880 | 160 | 18.18 | 19,223 | 5,696 | 29.63 | 1.47 | [0.88–2.48] | 0.142 | |
30–39 | 880 | 216 | 24.55 | 19,223 | 5,071 | 26.38 | 2.24 | [1.34–3.74] | 0.002 | |
40–49 | 880 | 166 | 18.86 | 19,223 | 3,052 | 15.88 | 2.86 | [1.70–4.80] | <0.001 | |
50–59 | 880 | 117 | 13.30 | 19,223 | 1,968 | 10.24 | 3.12 | [1.84–5.30] | <0.001 | |
60–69 | 880 | 101 | 11.48 | 19,223 | 1,251 | 6.51 | 4.24 | [2.48–7.23] | <0.001 | |
70–79 | 880 | 72 | 8.18 | 19,223 | 919 | 4.78 | 4.11 | [2.37–7.13] | <0.001 | |
80+ | 880 | 32 | 3.64 | 19,223 | 426 | 2.22 | 3.94 | [2.14–7.27] | <0.001 |
*From Wald test.