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. 2019 Feb 15;14(2):e0211972. doi: 10.1371/journal.pone.0211972

Table 3. Univariable analysis of reinfection cases >16 years of age, London, 2009–2015.

Exposure Reinfection TB cases Non- Reinfection TB cases Odds Ratio 95% confidence interval p*
Total Exposed % Total Exposed %
Sex Male 880 492 55.91 19,220 11,309 58.84 0.89 [0.77–1.02] 0.084
Social risk factors Any risk factors 766 125 16.32 17,029 1,739 10.21 1.71 [1.40–2.10] <0.001
Homelessness 841 46 5.47 18,229 617 3.38 1.65 [1.19–2.25] 0.001
Prison history 836 40 4.78 18,179 452 2.49 1.97 [1.38–2.75] <0.001
Drug use 834 45 5.4 18,140 661 3.64 1.51 [1.08–2.06] 0.009
Alcohol use 776 54 6.96 17,213 742 4.31 1.66 [1.22–2.21] <0.001
Site of disease CNS* TB 880 104 11.82 19,223 2,258 11.75 1.01 [0.81–1.24] 0.948
Time since entry into UK UK born 803 111 13.82 16,883 2,692 15.95 Reference
0–1 years 803 69 8.59 16,883 2,551 15.11 0.66 [0.48–0.89] 0.007
2–5 years 803 110 13.7 16,883 4,105 24.31 0.65 [0.50–0.85] 0.002
6–10 years 803 157 19.55 16,883 2,749 16.28 1.39 [1.08–1.78] 0.01
11+ years 803 356 44.33 16,883 4,786 28.35 1.80 [1.45–2.24] <0.001
Ethnic group Indian 879 230 26.17 19,041 5,734 30.11 Reference
White 879 108 12.29 19,041 2,097 11.01 1.28 [1.02–1.62] <0.001
Black Caribbean 879 19 2.16 19,041 640 3.36 0.74 [0.46–1.19] 0.214
Black African 879 233 26.51 19,041 4,160 21.85 1.40 [1.16–1.68] <0.001
Pakistani 879 89 10.13 19,041 1,899 9.97 1.17 [0.91–1.50] 0.223
Bangladeshi 879 41 4.66 19,041 1,130 5.93 0.90 [0.64–1.27] 0.561
Mixed/other 879 159 18.09 19,041 3,381 17.76 1.17 [0.95–1.44] 0.131
World region of birth West Europe 841 130 15.46 18,496 3,140 16.98 Reference
Central Europe 841 28 3.33 18,496 586 3.17 1.15 [0.76–1.75] 0.501
East Asia 841 8 0.95 18,496 193 1.04 1.00 [0.48–2.07] 0.997
East Europe 841 9 1.07 18,496 153 0.83 1.42 [0.71–2.85] 0.322
East Mediterranean 841 8 0.95 18,496 153 0.83 1.26 [0.61–2.63] 0.532
North Africa 841 14 1.66 18,496 184 0.99 1.84 [1.04–3.25] 0.037
North America & Oceania 841 0 0 18,496 42 0.23 1.00
South Asia 841 348 41.38 18,496 8,769 47.41 0.96 [0.78–1.18] 0.686
South East Asia 841 36 4.28 18,496 603 3.26 1.44 [0.99–2.11] 0.059
South, Central America & Caribbean 841 12 1.43 18,496 423 2.29 0.69 [0.38–1.25] 0.217
Sub-Saharan Africa 841 245 29.13 18,496 4,110 22.22 1.44 [1.16–1.79] 0.001
Unknown 841 3 0.36 18,496 140 0.76 0.52 [0.16–1.65] 0.265
Age group 16–19 880 16 1.82 19,223 840 4.37 Reference
20–29 880 160 18.18 19,223 5,696 29.63 1.47 [0.88–2.48] 0.142
30–39 880 216 24.55 19,223 5,071 26.38 2.24 [1.34–3.74] 0.002
40–49 880 166 18.86 19,223 3,052 15.88 2.86 [1.70–4.80] <0.001
50–59 880 117 13.30 19,223 1,968 10.24 3.12 [1.84–5.30] <0.001
60–69 880 101 11.48 19,223 1,251 6.51 4.24 [2.48–7.23] <0.001
70–79 880 72 8.18 19,223 919 4.78 4.11 [2.37–7.13] <0.001
80+ 880 32 3.64 19,223 426 2.22 3.94 [2.14–7.27] <0.001

*From Wald test.