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. 2018 Jun 21;2018(6):CD007105. doi: 10.1002/14651858.CD007105.pub4

Tecirli 2014.

Methods Double‐blinded (participant/outcome assessor), randomized clinical trial
Sequence generation not described
Follow‐up: 3 months
Participants Participants: 60 women in university hospital in Ankara, Turkey
Operation: radical mastectomy (with axillary lymph node dissection)
Groups, size: 30/30
Age: not listed
All female participants
Comorbidities: not listed
Interventions Group 1 (bupivacaine): intra‐op: intercostobrachial nerve was blocked with 10 cc 0.5% bupivacaine before being sectioned
Group 2 (control): intra‐op: intercostobrachial nerve sectioned without blockage
Adjuvants: none
Immediate post‐op pain control: no difference
Outcomes Continuous: VAS at 3 months
Dichotomus: pain questionnaire at 3 months
Other reported: analgesic consumption
Adverse events: reported as none
Notes Pain score ≥ 4 was accepted as pain
Funding sources: no explanation of financial support
Conflicts of interest: no conflict of interest statement given
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Unclear risk Sequence generation not explained
Allocation concealment (selection bias) Unclear risk Concealment of allocation not explained
Blinding of participants and personnel (performance bias) 
 All outcomes Unclear risk Blinding of medical personnel not explained
Blinding of outcome assessment (detection bias) 
 All outcomes Unclear risk Knowledge of outcome assessors not indicated
Incomplete outcome data (attrition bias) 
 All outcomes Low risk All participants completed the follow‐up evaluation
Selective reporting (reporting bias) Low risk No subgroup analysis or selective reporting was noted
Null bias Low risk Quote: "this study shows that intercostobrachial nerve block is an effective method to reduce the chronic neuropathic pain development after a breast cancer surgery."