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(A) Chemical structure of polymersomes with disulfide linkage. (B) Confocal laser scanning microscopy images of HeLa cells incubated for 2 h with (a & b) doxorubicin-loaded polymersomes without disulfide linkage and (c & d) doxorubicin-loaded polymersomes with disulfide linkage [red: doxorubicin (DOX), blue: 4’,6-diamidino-2-phenylindole (DAPI), pink: overlay of DOX and DAPI, scale bar: 20 μm]. Adapted with permission.[138]
