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. Author manuscript; available in PMC: 2019 Mar 18.
Published in final edited form as: Oncogene. 2018 Sep 18;38(7):1121–1135. doi: 10.1038/s41388-018-0498-3

Figure 6. INPP4B is required for optimal expression of a subset of AR target genes in mouse prostate.

Figure 6.

Whole prostates were dissected from 2 month old WT (N=11) and Inpp4b−/− (N=11) males and expression levels of Apof (A), Nkx 3.1 (B), Msmb (C), Pten (D), Pbsn (E) and Clu (F) were compared by RT-qPCR. (G) Histology of a 1 year old WT mouse prostate. (H-J) Examples of histology of 1 year old Inpp4b−/− mouse prostate. Examples of major HG PIN architectural patterns are shown: tufting (H), micropapillary structures lacking fibrovascular core (I), and cribriform formations (J). * p < 0.05, ** p < 0.01