Table 2. Univariate associations between AMD status across race and within race.
| Characteristic | No AMD | AMD | p |
|---|---|---|---|
|
All |
No AMD (n=133) |
AMD (n=90)* |
p |
| Age |
70.6 (6.30) |
77.8 (8.33) |
<0.001 |
| Sex (Male) |
51 (38.4) |
38 (42.2) |
0.562 |
| Race (EUR) |
81 (60.9) |
83 (92.2) |
<0.001 |
| Smoking (Ever) |
34 (25.6) |
31 (34.4) |
0.152 |
| C3a |
95.3 (34.3) |
113.1 (58.8) |
0.032 |
| C5a |
103.7 (23.9) |
93.1 (24.4) |
0.002 |
| Bb |
94.7 (42.5) |
116.6 (71.5) |
0.007 |
| Factor H |
98.3 (52.1) |
104.8 (63.2) |
0.864 |
|
AFR |
No AMD (n=52) |
AMD (n=7) |
p |
| Age |
70.9 (6.95) |
70.9 (10.4) |
0.993 |
| Sex (Male) |
20 (38.5) |
2 (28.6) |
0.702 |
| Smoking (Ever) |
9 (17.3) |
3 (42.9) |
0.141 |
| C3a |
96.1 (29.3) |
115.7 (55.0) |
0.371 |
| C5a |
112.3 (24.6) |
92.3 (26.1) |
0.045 |
| Bb |
93.5 (35.7) |
94.1 (49.1) |
0.592 |
| Factor H |
95.9 (58.9) |
135.9 (73.1) |
0.103 |
|
EUR |
No AMD (n=81) |
AMD (n=83)* |
p |
| Age |
70.6 (6.03) |
78.3 (7.94) |
<0.001 |
| Sex (Male) |
31 (38.3) |
36 (43.4) |
0.506 |
| Smoking (Ever) |
25 (30.9) |
28 (33.7) |
0.694 |
| C3a |
94.8 (37.3) |
112.9 (59.5) |
0.038 |
| C5a |
98.1 (21.8) |
93.1 (24.5) |
0.17 |
| Bb |
95.4 (46.6) |
118.5 (73.0) |
0.004 |
| Factor H | 99.9 (47.5) | 102.1 (62.0) | 0.946 |
Continuous variables are reported as mean (SD) and categorical variables are reported as n (%).*One patient missing all complement data.