Table 4. Multivariable logistic regression model of AMD status across all participants in the study.

Variable	Odds Ratio (95% CI)	p
Race (EUR versus AFR)	5.52 (2.16, 14.01)	<0.001
C3a (10 units increase)	1.10 (1.02, 1.19)	0.019
C5a (10 units increase)	0.83 (0.72, 0.97)	0.016
Age (years)	See Below	<0.001
Age x CFH activity	See Below	0.058
Age (10 year increase)
If CFH activity is 60	3.71 (2.06, 6.69)
If CFH activity is 90	2.90 (1.80, 4.65)
If CFH activity is 120	2.26 (1.45, 3.53)

Results for race are reported as odds ratio of AMD for EUR participants relative to AFR participants. Results for C3a and C5a that are not in an interaction are reported as odds ratios estimated for a specific increase in complement levels. Results for CFH activity are reported as odds ratios for a specific increase in CFH activity at specific patient ages. Similarly, results for age are reported as odds ratios for a specific increase in Age at specific levels of CFH activity to account for the interaction between age and CFH activity observed in the model. P values reported in the table are for the estimated regression coefficient from the model.