Table 3.
Fatigue, health status, and depression in women with and without TI
| Women with TI (N = 18) |
Women without TI (N = 31) |
P value | CI 95% |
||
|---|---|---|---|---|---|
| Lower | Upper | ||||
| Fatigue | |||||
| MFI subscales | |||||
| General fatigue | 13.22 (4.66) | 11.32 (5.15) | 0.17 | –1.10 | 4.87 |
| Physical fatigue | 12.11 (5.13) | 8.55 (4.94) | 0.02 | 0.58 | 6.55 |
| Reduced activity | 10.83 (4.82) | 8.58 (3.81) | 0.097 | –0.25 | 4.76 |
| Reduced motivation | 10.22 (4.51) | 8.16 (3.63) | 0.14 | –0.31 | 4.43 |
| Mental fatigue | 11.78 (5.09) | 9.19 (4.90) | 0.08 | –0.37 | 5.55 |
| MFI total score | 58.17 (20.33) | 45.81 (17.99) | 0.04 | 1.11 | 23.61 |
| Clinically significant fatigue (N, %)∗ | 11 (61%) | 9 (29%) | 0.03 | ||
| Health status | |||||
| SF-36 subscales | |||||
| Physical function | 75.83 (24.09) | 84.51 (21.34) | 0.06 | –22.02 | 4.66 |
| Social function | 65.97 (30.26) | 75.81 (24.78) | 0.27 | –25.86 | 6.20 |
| Physical role function | 44.44 (47.40) | 62.90 (41.27) | 0.20 | –44.44 | 7.52 |
| Emotional role function | 51.85 (46.05) | 58.06 (43.86) | 0.64 | –32.83 | 20.41 |
| Mental health | 66.35 (22.81) | 68.64 (18.91) | 0.71 | –14.65 | 10.07 |
| Vitality | 50.59 (25.43) | 60.84 (21.65) | 0.13 | –23.89 | 4.10 |
| Bodily pain | 71.72 (23.9) | 73.83 (25.17) | 0.76 | –16.85 | 12.62 |
| General health perception | 48.11 (23.10) | 59.13 (25.23) | 0.14 | –25.60 | 3.57 |
| MOS–HIV subscales | |||||
| Health distress | 57.11 (23.95) | 67.74 (19.15) | 0.09 | –23.16 | 1.90 |
| Cognitive function | 58.89 (22.66) | 71.29 (17.27) | 0.04 | –23.96 | –.84 |
| Depression | |||||
| BDI-II | |||||
| Total score BDI-II | 18.11 (16.65) | 11.81 (8.97) | 0.15 | –2.48 | 15.09 |
| Clinical depression, N (%)† | 7 (39%) | 5 (16%) | 0.07 | ||
BDI = Beck Depression Inventory; MFI = Multidimensional Fatigue Inventory; MOS-HIV = Medical Outcomes Study HIV Health Survey; SF-36 = Studies Short Form 36-item health survey; TI = testosterone insufficiency.
∗
MFI total score ≥53.
†
BDI-II total score ≥20.