Table 2.

Classification of fast dissolving technologies for the production of orodispersible dosage formulations

Property	ODT		ODF
	Lyophilized system	Compressed tablet–based system
Composition	Solution or suspension of drug with excipients	Active pharmaceutical ingredient with super-disintegrants	Hydrophilic polymers with drug and other excipients
Technology used	Lyophilization	Direct compression	Solvent casting, hot melt extrusion
Characteristics	High porosity that allows rapid water or saliva penetration and disintegration	Different levels of hardness and friability that results in varying disintegration and packaging needs	Large surface area leads to rapid disintegration
Packaging	Blister pack	High-density polyethylene bottles	Blister cards with multi-units

ODF = orodispersible film; ODT = orodispersible tablet.

Table adapted with permission from Wolters Kluwer, from Bala et al.²⁰