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. 2019 Feb 8;3(2):nzy096. doi: 10.1093/cdn/nzy096

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© 2019 Sheftel et al.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

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The fraction of the variation in tissue VA concentration from all sources explained by chylomicron deposition in ANCOVA, measured as α-VA concentration, both determined by HPLC (liver) or UPLC (adipose). Dietary treatment was added as a covariate to control for different quantities of preformed VA [0 (●, ); 0.5 (■, —); 1 (▲, – – –) μg/g feed] in each group. (A) α-VA concentrations explained >60% (P < 0.001) of the variation in VA concentration in liver. Data points with open symbols were from gerbils which were included in the EPI analysis but lacked RP samples. (B, C) α-VA concentration explained 15% (P = 0.012; B, epididymal) and 25% (P = 0.004; C, retroperitoneal) of the variation in retinol concentration in adipose. EPI, epididymal adipose; RP, retroperitoneal adipose; UPLC, ultra-performance LC; VA, vitamin A.

Inline graphic — The fraction of the variation in tissue VA concentration from all sources explained by chylomicron deposition in ANCOVA, measured as α-VA concentration, both determined by HPLC (liver) or UPLC (adipose). Dietary treatment was added as a covariate to control for different quantities of preformed VA [0 (●, ); 0.5 (■, —); 1 (▲, – – –) μg/g feed] in each group. (A) α-VA concentrations explained >60% (P < 0.001) of the variation in VA concentration in liver. Data points with open symbols were from gerbils which were included in the EPI analysis but lacked RP samples. (B, C) α-VA concentration explained 15% (P = 0.012; B, epididymal) and 25% (P = 0.004; C, retroperitoneal) of the variation in retinol concentration in adipose. EPI, epididymal adipose; RP, retroperitoneal adipose; UPLC, ultra-performance LC; VA, vitamin A.