Fig. 5.
Characterization and functional enrichment of genes differentially expressed following chronic mild stress. Overlap of (A) DEGs and (B) significantly enriched GO biological processes for DEGs in the prefrontal cortex, hippocampus, hypothalamus, and whole blood. (C) GO biological processes associated with DEGs. Outer track: tissue; second track: overarching themes associated with GO processes; third track: tissues in which GO processes were found; inner track: overlap of processes, colors corresponding to overarching theme. n = 8 per group for brain regions; n = 7 controls vs. n = 9 UCMS group for blood. Enrichment analyses were performed using MetaCore and significance was set at Padj < 0.05. Information is available in tabular format (Datasets S3 and S4).