Table 2.
Genotype | HORTEGA | PIZARRA | SEGOVIA | |||||||
N | BMI (kg/m2) | Obesity OR (95% CI) | N | BMI (kg/m2) | Obesity OR (95% CI) | N | BMI (kg/m2) | Obesity OR (95% CI) | ||
SDHC | AA | 1250 | 26.46±0.12 | 1 | 772 | 28.70±0.19 | 1 | 943 | 27.71±0.10 | 1 |
rs4600063 | AG-GG | 183 | 26.16±0.30 | 0.82 (0.55 to 1.22) | 96 | 27.86±0.04 | 0.47 (0.28 to 0.78) | 132 | 27.21±0.30 | 0.88 (0.57 to 1.36) |
HWE: 1 | P value | 0.9 | 0.33 | 0.071 | 0.0025 | 0.22 | 0.57 | |||
NDUFS1 | TT | 1308 | 26.41±0.12 | 1 | 799 | 28.49±0.10 | 1 | 1028 | 27.56±0.10 | 1 |
rs3770989 | CT-CC | 114 | 26.62±0.44 | 1.13 (0.72 to 1.77) | 77 | 29.85±0.60 | 1.5 (0.91 to 2.48) | 65 | 27.92±0.60 | 1.28 (0.73 to 2.23) |
HWE: 1 | P value | 0.34 | 0.6 | 0.016 | 0.12 | 0.48 | 0.39 | |||
NDUFS2 | AA | 1045 | 26.37±0.13 | 1 | 640 | 28.61±0.21 | 1 | 830 | 27.55±0.15 | 1 |
rs1136224 | AG-GG | 369 | 26.59±0.23 | 1.43 (1.09 to 1.89) | 223 | 28.59±0.34 | 1.10 (0.79 to 1.54) | 241 | 27.77±0.26 | 1.07 (0.76 to 1.48) |
HWE: 0.36 | P value | 0.25 | 0.011 | 0.71 | 0.58 | 0.42 | 0.71 | |||
NDUFS5 | CC-CG | 1309 | 26.47±0.12 | 1 | 832 | 28.63±0.10 | 1 | 947 | 27.6±0.14 | 1 |
rs11205591 | GG | 115 | 25.78±0.31 | 0.67 (0.41 to 1.10) | 38 | 27.66±0.70 | 0.86 (0.41 to 1.81) | 89 | 27.21±0.40 | 0.89 (0.53 to 1.5) |
HWE: 0.76 | P value | 0.049 | 0.11 | 0.38 | 0.69 | 0.25 | 0.66 | |||
SDHD | AA | 691 | 26.16±0.16 | 1 | 401 | 28.18±0.26 | 1 | 571 | 27.37±0.17 | 1 |
rs10891319 | AG-GG | 726 | 26.64±0.16 | 1.16 (0.90 to 1.49) | 478 | 29.00±0.24 | 1.22 (0.91 to 1.64) | 492 | 27.83±0.19 | 1.27 (0.96 to 1.68) |
HWE: 0.22 | P value | 0.08 | 0.25 | 0.084 | 0.18 | 0.077 | 0.095 |
BMI: mean±SD.
Bold: significant.
BMI, body mass index; HWE, Hardy-Weinberg equilibrium; N, number of individuals; SNP, single nucleotide polymorphism.