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. 2019 Feb 5;9(2):e027004. doi: 10.1136/bmjopen-2018-027004

Table 3.

SNP genotyping: distribution of BMI levels and the associated obesity risk for all genotypes in whole population

Gene/SNP Genotype N BMI (kg/m2) Non-obesity (N(%)) Obesity (N(%)) OR
(95% CI)
SDHC AA 2965 27.44±0.08 2109 (86.9) 851 (90.4) 1
rs4600063 AG-GG 411 26.89±0.21 318 (13.1) 90 (9.6) 0.72 (0.56 to 0.92)
P value 0.04 0.0072
SDHD AA 1663 27.06±0.11 1243 (51.3) 422 (45.4) 1
rs10891319 AG-GG 1696 27.60±0.11 1178 (48.7) 508 (54.6) 1.25 (1.08 to 1.46)
P value 0.0004 0.0038
NDUFS1 TT 3135 27.32±0.08 2273 (92.9) 857 (91.2) 1
rs3770989 CT-CC 256 27.92±0.32 173 (7.1) 83 (8.8) 1.30 (0.99 to 1.72)
P value 0.026 0.066
NDUFS2 AA 2515 27.33±0.09 1833 (76.1) 680(73) 1
rs1136224 AG-GG 833 27.46±0.16 575 (23.9) 251(27) 1.20 (1.01 to 1.43)
P value 0.31 0.041
NDUFS5 CC-CG 3088 27.40±0.08 2219 (92.3) 863(94) 1
rs11205591* GG 242 26.60±0.24 184 (7.7) 55(6) 0.72 (0.52 to 0.99)
P value 0.0011 0.039

Bold: significant, p<0.05.

*tag-SNP.

BMI values are expressed as mean±SD. Results after adjustment for the following variables included in the model: age and gender.

N, number of individuals; SNP, single nucleotide polymorphism.