Table 3.
Gene/SNP | Genotype | N | BMI (kg/m2) | Non-obesity (N(%)) | Obesity (N(%)) | OR (95% CI) |
SDHC | AA | 2965 | 27.44±0.08 | 2109 (86.9) | 851 (90.4) | 1 |
rs4600063 | AG-GG | 411 | 26.89±0.21 | 318 (13.1) | 90 (9.6) | 0.72 (0.56 to 0.92) |
P value | 0.04 | 0.0072 | ||||
SDHD | AA | 1663 | 27.06±0.11 | 1243 (51.3) | 422 (45.4) | 1 |
rs10891319 | AG-GG | 1696 | 27.60±0.11 | 1178 (48.7) | 508 (54.6) | 1.25 (1.08 to 1.46) |
P value | 0.0004 | 0.0038 | ||||
NDUFS1 | TT | 3135 | 27.32±0.08 | 2273 (92.9) | 857 (91.2) | 1 |
rs3770989 | CT-CC | 256 | 27.92±0.32 | 173 (7.1) | 83 (8.8) | 1.30 (0.99 to 1.72) |
P value | 0.026 | 0.066 | ||||
NDUFS2 | AA | 2515 | 27.33±0.09 | 1833 (76.1) | 680(73) | 1 |
rs1136224 | AG-GG | 833 | 27.46±0.16 | 575 (23.9) | 251(27) | 1.20 (1.01 to 1.43) |
P value | 0.31 | 0.041 | ||||
NDUFS5 | CC-CG | 3088 | 27.40±0.08 | 2219 (92.3) | 863(94) | 1 |
rs11205591* | GG | 242 | 26.60±0.24 | 184 (7.7) | 55(6) | 0.72 (0.52 to 0.99) |
P value | 0.0011 | 0.039 |
Bold: significant, p<0.05.
*tag-SNP.
BMI values are expressed as mean±SD. Results after adjustment for the following variables included in the model: age and gender.
N, number of individuals; SNP, single nucleotide polymorphism.