Fig. 1. Higher temporal signal to noise ratio (TSNR) with ultra-high field 7-Tesla (7 T) functional magnetic resonance imaging (MRI) scales with echo time (TE) and is boosted by multi-echo based denoising.
a TSNR plotted for whole brain at 3-Tesla (3 T) and 7 T. b TSNR plotted for 7 T at 3 T for 4 different TE’s (TE1 = shortest, TE4 = longest). c Percent increase in TSNR at 7 T compared to 3 T scales with TE (Linear fit, adjusted R2 = 0.976, p = 0.008). d TSNR plotted for whole brain after multi-echo acquisition and denoising and traditional single-echo acquisition and denoising. ***p ≤ 0.001