Table 1.
Demographic and clinical characteristics
| 3 T | 7 T | |||
|---|---|---|---|---|
| MDD | HC | MDD | HC | |
| N | 15 | 17 | 10 | 17 |
| Age at enrollment, years (mean ± SD) | 40.7 ± 11.560 | 37.4 ± 10.137 | 34.3 ± 11.186 | 38.41 ± 11.9 |
| Male (frequency, %) | 9, 60% | 12, 70.6% | 6, 60% | 9, 52.9% |
| White (frequency, %) | 8, 53.3% | 8, 47.1% | 6, 60% | 6, 46.2% |
| Hispanic ethnicity (frequency, %) | 6, 40% | 1, 5.9% | 2, 20% | 2, 15.4% |
| College degree, at least 2-year (frequency, %) | 12, 80% | 15, 88.3% | 8, 80% | 10, 76.9% |
| Employed, at least part-time (frequency, %) | 10, 66.7% | 14, 82.4% | 7, 70% | 11, 84.6% |
| Married (frequency, %) | 1, 6.7% | 3, 17.6% | 0% | 2, 15.4% |
| Age at first episode (mean ± SD) | 23.6 ± 13.695 | – | 22 ± 12.055 | – |
| Years since first episode (mean ± SD) | 17.1 ± 10.575 | – | 12.3 ± 6.913 | – |
| Number of episodes (median, range) | 1, 39 | – | 2.5, 48 | – |
| Duration of current MDE, months (median, range) | 120, 498 | – | 13.5, 190 | – |
| Recurrent MDD (frequency, %) | 4, 26.7% | – | 6, 60% | – |
| SHAPS Score (mean ± SD) | 35.27 ± 7.206 | 17.1 ± 4.293 | 39.6 ± 5.966 | 18.7 ± 4.9 |
| MADRS score (mean ± SD) | 28.4 ± 4.687 | 0.824 ± 1.131 | 29.8 ± 7.569 | 0.5 ± 0.9 |
Six of the 17 healthy control (HC) and 5 of the major depressive disorder (MDD) subjects completed both 3-Tesla (3 T) and 7-Tesla (7 T)
N number of subjects, MADRS Montgomery–Åsberg Depression Rating Scale, SHAPS Snaith-Hamilton Pleasure Scale, SD standard deviation