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. 2019 Feb 15;10(3):150. doi: 10.1038/s41419-019-1332-8

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — a Relative expression of lncRNA ZNFX1-AS1 in SW620 and LOVO cells after transfection with lncRNA ZNFX1-AS1 siRNAs (*P < 0.05). b CCK-8 assay was used to detect the viability in lncRNA ZNFX1-AS1 siRNA and scramble transfected CRC cells (*P < 0.05). c Colony formation assay was performed in CRC cells transfected with lncRNA ZNFX1-AS1 siRNAs and scramble (*P < 0.05). d The stable lncRNA ZNFX1-AS1 knockdown SW620 cells were used for the in vivo tumorigenesis assays. The tumors form the two groups of nude mice were shown. e The tumor volume were measured every 5 days, and the tumor growth curve was shown (*P < 0.05). f The tumor weight of the nude mice formed by sh-ZNFX1-AS1 and sh-NC cells (*P < 0.05). g Relative expression of lncRNA ZNFX1-AS1 in nude mice tissues formed by sh-ZNFX1-AS1 and sh-NC cells (*P < 0.05)