Fig. 2. Methylphenidate (MP) increased dopamine (DA) release in striatal areas as measured by the difference between BP_PL and BP_MP.

The SPM difference images were superimposed onto T2-weighted magnetic resonance images in coronal (left upper), sagittal (right upper), and transverse (left lower) views. The color bar indicates t score values. Red represents the highest value and dark violet represents the lowest value. The bar chart showed DA release (PL–MP) in striatal regions in cocaine use disorder and healthy controls