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. 2019 Feb 15;19:155. doi: 10.1186/s12885-019-5327-8

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — ROC curve demonstrating the sensitivity and specificity of the LGR5∆5 intratumoral mRNA level of patients who developed regional lymph node metastases compared to patients without metastasis. The cut-off point was 4.2 relative LGR5Δ5 mRNA level with a corresponding AUC (area under the curve) = 63.8% (p = 0.041; 95% CI: 0.5–0.8).