Table 2.
Antimicrobial susceptibility of S. pneumoniae isolated from children with AOM
| Antibiotic | Susceptible n (%) | Intermediate n (%) | Resistant n(%) | MIC50 (μg/mL) | MIC90 (μg/mL) |
|---|---|---|---|---|---|
| Penicillin Parenterala | 36 (97.3) | 1 (2.7) | 0 (0.0) | 0.15 | 1 |
| Penicillin Oral | 5 (13.5) | 22 (59.5) | 10 (27.0) | 0.15 | 1 |
| Vancomycin | 37 (100.0) | 0 (0.0) | 0 (0.0) | 0.5 | 0.5 |
| Erythromycin | 0 (0.0) | 1 (2.7) | 36 (97.3) | 1 | 2 |
| Levofloxacin | 36 (97.3) | 1 (2.7) | 0 (0.0) | 0.5 | 1 |
| Tetracycline | 1 (2.7) | 0 (0.0) | 36 (97.3) | 4 | 16 |
| Trimethoprim-sulfamethoxazole | 6 (16.2) | 3 (8.1) | 28 (75.7) | 0.5/0.95 | 0.5/0.95 |
| Linezolid | 37 (100.0) | 0 (0.0) | 0 (0.0) | 0.5 | 0.5 |
| Chloramphenicol | 34 (91.9) | 0 (0.0) | 3 (8.1) | 2 | 4 |
| Cefotaximea | 31 (83.8) | 4 (10.8) | 2 (5.4) | 1 | 2 |
AOM, acute otitis media
a2016 CLSI breakpoints were considered for nonmeningitis