Fig. 6.

PLAIDOH ranks LCPs by likely transcriptional regulatory mechanism, inferred from Enhancer and LncRNA Cis-regulatory Scores. a-f Plots show LCPs from ENCODE cell lines (a-c) or TCGA DLBC samples (d-f). a & d Plots show LCPs ranked by increasing LncRNA Transcript Cis-regulatory Scores. Red points are known cis-acting lncRNAs; in green are novel LCPs with the highest scores and/or containing known lymphoma oncogenes. b & e As in A&D, but ranked by increasing Enhancer Scores. Highlighted in red are known enhancer-associated lncRNAs; in green are novel LCPs with the highest scores and/or containing known lymphoma oncogenes. c & f XY plots show Enhancer versus LncRNA Transcript Cis-regulatory Scores segregating LCPs. Dotted lines in a-f reflect score cut-offs based on the geometric inflection points calculated from the data in a, b, d & e. Red and green data points are from a & b (for c), or d & e (for f)