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Number of adverse effects of CBZ treatment
| Total (n = 118) | High (n = 37) | Low (n = 81) | P (High vs Low) | |
|---|---|---|---|---|
| Grade 4 neutropenia | 53 (45%) | 24 (65%) | 29 (36%) | < 0.001* |
| Febrile neutropenia | 30 (25%) | 13 (35%) | 17 (21%) | 0.118 |
| Grade 3 thrombocytopenia | 9 (8%) | 6 (16%) | 3 (4%) | 0.026* |
| Grade 3 nausea | 17 (14%) | 5 (14%) | 12 (15%) | 1 |
| Grade 2 diarrhea | 13 (11%) | 4 (11%) | 9 (11%) | 1 |
| Grade 2 malaise | 19 (16%) | 4 (11%) | 16 (20%) | 0.296 |
| Pneumonia | 5 (4%) | 2 (5%) | 3 (4%) | 0.648 |
*P < 0.05
