Table 1. The top gene candidates, ordered by levels of significance, following the clustering analysis of unique, deleterious variants.

Gene	Variants	P value	Samples	Cumulative sample count
NOTCH1	31	<2.22 x 10-16	37	37
FLT4	22	4.44 x 10-16	21	57
RYR1	21	1.43 x 10-06	22	78
TBX1	8	6.50 x 10-05	8	86
ZFPM1	11	0.000266817	12	98
ZNF717	9	0.001125519	10	106
DLX6	7	0.002583786	8	114
PCM1	11	0.003208801	11	123
CAMTA2	9	0.007243157	9	129