Skip to main content
. Author manuscript; available in PMC: 2019 Jul 21.
Published in final edited form as: Nat Chem Biol. 2019 Jan 21;15(3):269–275. doi: 10.1038/s41589-018-0209-y

Figure 5: Proposed models for the coordination of junction resolution, conformer exchange and branch migration.

Figure 5:

a, Schematic of a kinetic model deduced to describe the dynamics of resolving-enzyme-bound HJs. PD serves as an intermediate that allows a resolving-enzyme-bound junction to undergo both branch migration and conformer exchange. b, Schematic of the speculative ternary complex containing the branch migration-facilitating enzyme, the junction resolving enzyme and Holliday junction for the coordination of branch migration and junction resolution.