Skip to main content
. Author manuscript; available in PMC: 2020 Feb 15.
Published in final edited form as: Cancer Res. 2018 Dec 27;79(4):807–818. doi: 10.1158/0008-5472.CAN-18-2209

Figure 5.

Figure 5.

Pep8 increases cellular senescence in Rbm38- and p53-dependent manners. A Immunoblots for wild-type, Rbm38- and p53-null MCF7 cells treated with 5 μM Pen-Ctrl or Pen-Pep8 with and without 6.25 ng/mL doxorubicin for 18 h. B SA-ß-gal staining of wild-type, Rbm38- and p53-null MCF7 cells after treatment with 5 μM Pen-Ctrl or Pen-Pep8 with and without 6.25 ng/mL doxorubicin for 18 h. C Quantification of SA-ß-gal positive cells as shown in B. Values represent the mean ± SEM of three independent experiments (* p= 0.009, ** p= 0.0006, *** p= 0.0001). All western blot figures are representative data of at least 2 independent replicates.