Table 2.
Significant relationshipsa between inflammatory cytokines following LPS stimulation and clinical measures within the psychiatric group
| SHAPSb | ||
|---|---|---|
| Cytokine | Correlation (ρ) | p-value |
| FGF-2 | .421 | .004 |
| Flt3-L | .513 | .000 |
| Fractalkine | .572 | .000 |
| G-CSF | .570 | .000 |
| GM-CSF | .488 | .001 |
| IL-1α | .436 | .002 |
| IL-2 | .349 | .018 |
| IL-3 | .387 | .008 |
| IL-4 | .379 | .009 |
| IL-7 | .479 | .001 |
| IL-9 | .419 | .004 |
| IL-10 | .334 | .023 |
| IL-12p40 | .372 | .011 |
| IL-12p70 | .542 | .000 |
| IL-15 | .548 | .000 |
| IL-17α | .370 | .011 |
| MCP-3 | .350 | .017 |
| TNF-β | .371 | .011 |
| VEGF | .506 | .000 |
SHAPS = Snaith-Hamilton Pleasure Scale; FGF = fibroblast growth factor; Flt3-L = fms-like tyrosine kinase-3 ligand; G-CSF = granulocyte colony-stimulating factor; GM-CSF = granulocyte-macrophage colony-stimulating factor; IL = interleukin; MCP = monocyte chemotactic protein; TNF = tumour necrosis factor; VEGF = vascular endothelial growth factor.
a
at the FDR correction threshold;
b
controlling for BDI with anhedonia item removed, body mass index, age, and sex.