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. Author manuscript; available in PMC: 2020 Feb 15.
Published in final edited form as: Clin Cancer Res. 2018 Sep 18;25(4):1291–1301. doi: 10.1158/1078-0432.CCR-18-2392

Figure 6. Schema of HSD17B2 function and regulation.

Figure 6.

17βHSD2 inactivates T and DHT to prevent disease progression. DNA methylation, androgen stimulation and alternative splicing were involved in HSD17B2 functional silencing.