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. Author manuscript; available in PMC: 2019 Feb 17.
Published in final edited form as: Genet Med. 2016 Oct 13;19(6):643–651. doi: 10.1038/gim.2016.158

Figure 1. Deletion mapping in families OGI-046 and OGI-023.

Figure 1

A) A heterozygous deletion of 20 genes on chr2q12.1 found in family OGI-046 by CGH and SNP arrays, and validated by SNPs found in WES B) Pedigree of family OGI-046 with mutant allele segregation indicated. C) Fine mapping of the deletion by qPCR in family OGI-046. D) Pedigree of family OGI-023 with mutant allele segregation indicated. E) Fine mapping of the deletion by qPCR in family OGI-023. Each primer pair in the qPCR experiments was normalized to two reference genes GPR15 and ZNF80, where the error bars represent standard deviation between these results.