Table 4.

Mean changes (reduction) in primary and secondary parameters from baseline to week 12.

Parameters	FAS population
	IQP-AE-103 LD (N=35)		IQP-AE-103 HD (N=35)		Placebo (N=31)
	Mean ± s.d.	p values, vs. placebo	Mean ± s.d.	p values, vs. placebo	Mean ± s.d.
Body weight (kg)	3.01 ± 2.19	<0.001	5.03 ± 2.50	<0.001	0.98 ± 2.06
BMI (kg/m2)	1.09 ± 0.75	<0.001	1.75 ± 0.83	<0.001	0.34 ± 0.77
Waist circumference (cm)	2.5 ± 2.4	0.001	4.1 ± 3.3	<0.001	0.9 ± 1.6
Hip circumference (cm)	2.8 ± 2.5	0.001	4.0 ± 3.0	<0.001	0.9 ± 1.2
Body fat mass (kg)	2.62 ± 3.83	0.005	3.15 ± 2.41	<0.001	0.23 ± 2.74
Fat-free mass (kg)	0.39 ± 3.68	0.931	1.80 ± 2.38	0.124	0.75 ± 2.93

FAS = full analysis set; LD = low dose; HD = high dose.