Table 5.
Summary of changes in laboratory measurements during the study.
| Measurements | Pre- to poststudy changes | |||
|---|---|---|---|---|
| Low-dose IQP-AE-103 (mean ± s.d.) | High-dose IQP-AE-10 (mean ± s.d.) | Placebo (mean ± s.d.) | p value∗ | |
| Hemoglobin (mmol/l) | −0.08 ± 0.48 | 0.09 ± 0.63 | −0.04 ± 0.75 | NS |
| Hematocrit (l/l) | −0.003 ± 0.029 | −0.003 ± 0.028 | −0.001 ± 0.036 | NS |
| Erythrocytes (Tpt/l) | 0.01 ± 0.31 | 0.02 ± 0.34 | −0.02 ± 0.38 | NS |
| Thrombocytes (Gpt/l) | 8.6 ± 40.5 | 2.3 ± 42.1 | 0.8 ± 56.7 | NS |
| Leukocytes (Gpt/l) | 0.08 ± 1.55 | −0.33 ± 1.65 | 0.16 ± 1.63 | NS |
| Mean cell volume (fl) | −0.5 ± 3.5 | −1.2 ± 5.4 | 0.1 ± 3.8 | NS |
| Mean corpuscular hemoglobin (fmol/Ery) | −0.021 ± 0.058 | 0.013 ± 0.082 | 0.001 ± 0.076 | NS |
| Mean corpuscular hemoglobin concentration (mmol/l) | −0.09 ± 0.95 | 0.24 ± 0.87 | 0.03 ± 0.96 | NS |
| Alanine aminotransferase (μkat/l) | −0.075 ± 0.168 | −0.035 ± 0.204 | 0.004 ± 0.211 | NS |
| Aspartate aminotransferase (μkat/l) | −0.172 ± 0.483 | −0.137 ± 0.566 | 0.028 ± 0.174 | NS |
| Alkaline phosphatase (μkat/l) | 0.026 ± 0.194 | −0.150 ± 0.522 | 0.055 ± 0.305 | NS |
| γ-Glutamyl transferase (μkat/l) | −0.083 ± 0.205 | −0.042 ± 0.161 | 0.052 ± 0.346 | NS |
| Bilirubin (μmol/l) | 0.02 ± 6.76 | 4.35 ± 9.15 | 1.19 ± 7.89 | NS |
| Creatinine (mmol/l) | 0.26 ± 13.58 | 3.98 ± 9.37 | 1.92 ± 12.17 | NS |
| Urea (mmol/l) | −0.17 ± 1.44 | 0.07 ± 1.24 | −0.19 ± 1.32 | NS |
| Uric acid (μmol/l) | −1.8 ± 60.9 | −6.4 ± 77.3 | 11.7 ± 67.2 | NS |
| Glucose (mmol/l) | −0.01 ± 0.63 | 0.01 ± 0.92 | −0.16 ± 0.54 | NS |
| Vitamin A (mg/l) | −0.002 ± 0.149 | 0.020 ± 0.173 | 0.063 ± 0.142 | NS |
| Vitamin D (ng/l) | 3.51 ± 13.45 | 4.37 ± 10.41 | 3.66 ± 11.79 | NS |
| Vitamin E (mg/l) | −0.81 ± 3.11 | −0.61 ± 3.07 | 1.09 ± 3.78 | NS |
| Vitamin K (μg/l) | 0.013 ± 1.197 | 0.086 ± 0.690 | 0.050 ± 0.689 | NS |
| Vitamin K2mK4 (μg/l) | −0.002 ± 0.152 | −0.022 ± 0.154 | −0.031 ± 0.114 | NS |
| Vitamin K2mK7 (μg/l) | 0.143 ± 0.402 | −0.157 ± 1.942 | −0.086 ± 0.507 | NS |
| Total cholesterol (mmol/l) | −0.08 ± 0.84 | −0.30 ± 1.12 | 0.18 ± 1.09 | NS |
| High-density lipoprotein cholesterol (mmol/l) | 0.00 ± 0.39 | 0.10 ± 0.32 | 0.02 ± 0.39 | NS |
| Low-density lipoprotein cholesterol (mmol/l) | −0.02 ± 0.77 | −0.34 ± 1.04 | 0.03 ± 0.86 | NS |
| Triglycerides (mmol/l) | 0.00 ± 0.79 | −0.09 ± 0.76 | 0.13 ± 0.39 | NS |
| HbA1c (%) | 0.14 ± 0.35 | 0.03 ± 0.34 | 0.11 ± 0.20 | NS |
∗ p Values from the Kruskal–Wallis test.