Table 1.
Baseline data for high-throughput gene screening and RT-qPCR validation in the healthy control and CGA groups.
| Indicators | Healthy control group (n = 30) | CGA group (n = 60) |
P-value |
|---|---|---|---|
| Age | 50.00 ± 8.90 | 50.80 ± 9.00 | 0.691 |
| Gender (% of males) | 28 (93.33) | 56 (93.33) | 1.000 |
| BMI (kg/m2) | 25.20 ± 1.10 | 25.50 ± 1.30 | 0.281 |
| Systolic pressure (mmHg) | 132.00 ± 8.00 | 133.00 ± 7.00 | 0.544 |
| Diastolic pressure (mmHg) | 76.00 ± 6.00 | 77.00 ± 6.00 | 0.458 |
| FBG (mmol/L) | 5.10 ± 0.60 | 5.20 ± 0.50 | 0.406 |
| TC (mmol/L) | 4.90 ± 0.50 | 5.10 ± 0.50 | 0.077 |
| TG (mmol/L) | 2.10 ± 0.80 | 2.20 ± 0.90 | 0.608 |
| ALT (U/L) | 30.00 ± 9.00 | 31.10 ± 8.50 | 0.572 |
| AST (U/L) | 25.20 ± 7.80 | 26.80 ± 8.30 | 0.382 |
| eGFR(ml/min/1.73m2) | 111.00 ± 6.50 | 110.00 ± 7.50 | 0.392 |
| SUA (μmol/L) | 330.00 ± 70.00 | 529.00 ± 76.00 | < 0.001 |
| ESR (mm/h) | 10.00 ± 5.50 | 33.00 ± 15.70 | < 0.001 |
| CRP (mg/L) | 3.10 ± 2.20 | 22.20 ± 11.70 | < 0.001 |
| Pain scores | 0 | 3.60 ± 0.80 | - |
| Swelling scores | 0 | 1.90 ± 0.89 | - |
| Restricted movement scores | 0 | 1.90 ± 0.90 | - |
CGA: chronic gouty arthritis; BMI: body mass index; FBG: Fasting blood-glucose; TC: total cholesterol; TG: triglyceride; ALT: alanine aminotransferase; AST: aspartate aminotransferase; eGFR: estimate glomerular filtration rate; SUA: serum uric acid; ESR: erythrocyte sedimentation rate; CRP: C-reactive protein.