Table 3.
Baseline information of patients in the 3 groups.
| Indicators | Control group (n = 52) |
Allopurinol group (n = 55) |
Chuanhutongfeng mixture group (n = 58) | P-value |
|---|---|---|---|---|
| Age | 49.90 ± 9.00 | 50.50 ± 8.90 | 51.10 ± 9.10 | 0.784 |
| Gender (% of males) | 50 (96.15) | 53 (96.36) | 55 (94.83) | 0.908 |
| BMI (kg/m2) | 25.33 ± 1.12 | 25.46 ± 1.06 | 25.50 ± 1.26 | 0.726 |
| Systolic pressure (mmHg) | 133.00 ± 7.00 | 132.00 ± 8.00 | 134.00 ± 7.00 | 0.354 |
| Diastolic pressure (mmHg) | 76.00 ± 5.00 | 75.00 ± 7.00 | 75.00 ± 6.00 | 0.618 |
| Disease duration (years) | 9.90 ± 5.11 | 9.91 ± 5.42 | 9.87 ± 5.50 | 0.999 |
| Tophus (n, %) | 26 (50.00) | 28 (50.91) | 30 (51.72) | 0.984 |
| FBG (mmol/L) | 5.12 ± 0.58 | 5.21 ± 0.46 | 5.17 ± 0.63 | 0.710 |
| TC (mmol/L) | 4.89 ±0.45 | 5.03 ± 0.46 | 5.10 ± 0.47 | 0.057 |
| TG (mmol/L) | 2.17 ± 0.85 | 2.21 ± 0.72 | 2.16 ± 0.81 | 0.940 |
| ALT (U/L) | 30.20 ± 9.50 | 29.50 ± 8.80 | 31.70 ± 8.40 | 0.406 |
| AST (U/L) | 25.10 ± 7.70 | 24.80 ± 7.40 | 27.90 ± 8.50 | 0.074 |
| eGFR(ml/min/1.73m2) | 110.10 ± 7.40 | 111.50 ± 7.50 | 110.40 ± 7.70 | 0.339 |
| SUA (μmol/L) | 532.00 ± 69.00 | 529.00 ± 72.00 | 530.00 ± 74.00 | 0.976 |
| ESR (mm/h) | 31.00 ± 14.20 | 33.90 ± 15.70 | 32.20 ± 16.30 | 0.622 |
| CRP (mg/L) | 21.30 ± 9.20 | 20.40 ± 10.80 | 22.00 ± 12.10 | 0.734 |
| Pain score | 3.54 ± 1.57 | 3.71 ±1.58 | 3.64 ±1.38 | 0.843 |
| Swelling score | 1.97 ± 0.89 | 1.97 ± 0.95 | 1.97 ± 0.88 | 1.000 |
| Restricted movement score | 1.98 ± 0.72 | 1.98 ± 0.89 | 1.99± 0.88 | 0.997 |
| CCL2 (pg/mL) | 538.00 ± 223.00 | 545.00 ± 175.00 | 572.00 ± 160.00 | 0.597 |
| CXCL8 (pg/mL) | 619.00 ± 199.00 | 643.00 ± 181.00 | 645.00 ± 218.00 | 0.757 |
| miR-486-5p | 2.51 ± 1.22 | 2.31 ± 1.19 | 2.24 ± 1.31 | 0.505 |
| miR-339-5p | 4.90 ± 1.98 | 4.93 ± 2.16 | 4.64 ± 2.18 | 0.725 |
| miR-361-5p | 3.27 ± 1.80 | 3.15 ± 1.77 | 2.98 ± 1.47 | 0.661 |
BMI: body mass index; FBG: Fasting blood-glucose; TC: Total cholesterol; TG: triglyceride; ALT: alanine aminotransferase; AST: aspartate aminotransferase; eGFR: estimate glomerular filtration rate; SUA: serum uric acid; ESR: erythrocyte sedimentation rate; CRP: C-reactive protein; CCL2: chemokine (C-C motif) ligand 2; CXCL8: chemokine (C-X-C motif) ligand 8.