Fig. 8.

Dex-PBMA with or without Tacrolimus coated or bare CoCr stent implantation in rabbit iliac artery restenosis model after 30 days (n=1, 3 animals, preliminary study). (A) Representative Hematoxylin-Eosin stainings (Up). L indicates the lumen, I the intima delimited by the lumen and internal elastic lamina (dashdotted line) and M the media delimited by the internal and the external elastic laminas (dashed line). Quantification of intimal hyperplasia (down) on Dex-PBMA (black bar), Dex-PBMA _TAC (grey bar) and CoCr (white) stents. Comparison of areas of the intima and media and the ratio of these last ones. (B) Difference of TNFα arterial blood concentration between before stent implantation and 30 days letter before sacrifice.