Table 3.
Brain Regions |
Microinfarct Measure |
Episodic Memory |
Semantic Memory |
Working Memory |
Visuospatial Ability |
Perceptual Speed |
---|---|---|---|---|---|---|
Cortical Watershed | Single | −0.11 (0.21, 0.60) |
−0.22 (0.23, 0.44) |
−0.06 (0.20, 0.78) |
−0.15 (0.20, 0.46) |
−0.24 (0.18, 0.20) |
Multiple | −0.35 (0.29, 0.22) |
−0.50 (0.31, 0.10) |
−0.58 (0.27, 0.03*) |
−0.57 (0.27, 0.03*) |
−0.08 (0.24, 0.75) |
|
Other Brain Regions | Single | 0.15 (0.15, 0.32) |
0.06 (0.17, 0.72) |
0.24 (0.14, 0.10) |
0.15 (0.14, 0.29) |
0.08 (0.13, 0.52) |
Multiple | −0.19 (0.21, 0.37) |
−0.17 (0.23, 0.46) |
−0.24 (0.20, 0.22) |
0.13 (0.20, 0.50) |
−0.15 (0.18, 0.41) |
Linear regression models with terms for age, sex, education, AD pathology summary score, and macroscopic infarcts. All models used trichotomous variables for microinfarct measures (none, single, and multiple). Values in cells are estimated coefficients (SE, p-value). Significant (p<0.05) associations indicated with an asterisk*