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. Author manuscript; available in PMC: 2019 Mar 1.
Published in final edited form as: Cancer. 2018 Dec 6;125(5):779–787. doi: 10.1002/cncr.31859

TABLE 3.

Multivariate Regression of Significant Demographic and Treatment Variables on Depression as Measured Using the Hospital Anxiety and Depression Scale

Depression (HADS-D)
Variable Regression Coefficient t P
CRP (log transformed) 0.42 (0.6) 4.232 <.001
Treatment type
 Chemotherapy Reference
 Immunotherapy −0.05 (0.8) −0.49 .63
 Targeted therapy −0.09 (1.0) −0.81 .42
Disease type
 Adenocarcinoma Reference
 Squamous cell carcinoma 0.05 (1.3) 0.49 .62
 Small cell carcinoma 0.19 (1.0) 1.97 .051

Abbreviations: CRP, C-reactive protein; HADS-D, Hospital Anxiety and Depression Scale–Depression Subscale.

F = 6.607; adjusted R2 = 0.226.