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. 2018 Dec 18;23(3):1917–1925. doi: 10.1111/jcmm.14093

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© 2018 The Authors. Journal of Cellular and Molecular Medicine published by John Wiley & Sons Ltd and Foundation for Cellular and Molecular Medicine.

This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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Detailed presentation of interactions between hsa_circRNA_101128 and its five potential miRNA targets. The 2D structure displayed the MRE sequence, pairing of miRNA target nucleotides and seed type. The “local AU” showed upstream and downstream of the seed sequence, black and red bars represented G/C and low accessibility as well as A/U and high accessibility of the seed, respectively, and bar height stands for the extent of accessibility. The position column showed the most likely relative MRE position on the linearized circRNA sequence. MRE, microRNA response elements