Table 2.

Genetic association between increased vitamin D levels and bone mineral density (BMD)

Dataset	Methods	OR/Intercept	SE	95% confidence interval_lower	P value
Total body	Weighted_median	0.88	0.066	[0.78, 1.00]	0.057
Total body	IVW	0.92	0.059	[0.82, 1.04]	0.17
Total body	MR‐Egger	0.84	0.105	[0.68, 1.03]	0.096
Total body	MR‐Egger intercept test	0.005	0.005	[−0.004, 0.014]	0.278
Total body (0‐15)	Weighted_median	0.89	0.153	[0.66, 1.20]	0.432
Total body (0‐15)	IVW	0.90	0.138	[0.69, 1.18]	0.44
Total body (0‐15)	MR‐Egger	0.84	0.245	[0.52, 1.35]	0.465
Total body (0‐15)	MR‐Egger intercept test	0.004	0.011	[−0.017, 0.025]	0.72
Total body (15‐30)	Weighted_median	0.97	0.272	[0.57, 1.65]	0.9
Total body (15‐30)	IVW	0.88	0.242	[0.55, 1.41]	0.595
Total body (15‐30)	MR‐Egger	0.83	0.436	[0.35, 1.95]	0.67
Total body (15‐30)	MR‐Egger intercept test	0.003	0.019	[−0.034, 0.04]	0.875
Total body (30‐45)	Weighted_median	0.75	0.168	[0.54, 1.04]	0.081
Total body (30‐45)	IVW	0.81	0.206	[0.54, 1.21]	0.308
Total body (30‐45)	MR‐Egger	0.80	0.41	[0.36, 1.78]	0.582
Total body (30‐45)	MR‐Egger intercept test	0.001	0.018	[−0.035, 0.037]	0.964
Total body (45‐60)	Weighted_median	0.83	0.129	[0.64, 1.07]	0.145
Total body (45‐60)	IVW	0.88	0.174	[0.63, 1.24]	0.476
Total body (45‐60)	MR‐Egger	0.63	0.278	[0.36, 1.08]	0.094
Total body (45‐60)	MR‐Egger intercept test	0.018	0.012	[−0.006, 0.043]	0.138
Total body (>60)	Weighted_median	1.02	0.113	[0.82, 1.28]	0.855
Total body (>60)	IVW	1.02	0.101	[0.84, 1.24]	0.851
Total body (>60)	MR‐Egger	1.14	0.18	[0.80, 1.62]	0.482
Total body (>60)	MR‐Egger intercept test	−0.006	0.008	[−0.021, 0.01]	0.47

IVW, Inverse‐variance weighted meta‐analysis.

The significance of suggestive association between vitamin D levels and BMD was at P < 0.05.

The significance of statistically significant association between vitamin D levels and BMD was at Bonferroni corrected significance P < 0.05/6 = 0.0083.