Table 1.
Groups | Intrasplenic implantation mouse modela | Orthotopic implantation mouse modela | Metastatic Rateb | P‐valueb | |
---|---|---|---|---|---|
Liver metastasis | Lung metastasis | Lymph node metastasis | |||
Tn+ | 3/6 | 1/6 | 5/5 | 9/11 | P* = 0.034 |
Tn‐ | 1/6 | 0/6 | 3/5 | 4/11 |
Distant metastases to specific organs or regional lymph nodes occurred in both mouse models.
There was a significantly increased incidence of metastasis in Tn‐positive cells implanted mice. (9 of 11 vs 4 of 11, P* < 0.05).