Figure 1.
Characteristics of αβ T-cell depleted grafts used as stem cell boosters (n = 12). (A) Log depletion of αβ T-cells and yield (recovery) of γδ T-cells in target fractions infused into patients (connected with dashed lines). (B) Analysis of cell subsets of interest in the αβ T-cell depleted cell products with (C) more detailed analysis of γδ subsets and invariant NKT-cells post-depletion gated on total T-cells. (D) Representative example plots of T-cells with αβ T-cell receptor (TCR), γδ TCR and γδ subsets are shown from patient 9 (all plots gated on total CD3+ T-cells).