Table 1.
Comparison of pre and post treatment values for GPx, MDA and SOD after crocin administration for 21 days in demyelinated rats. Data are presented as Mean ± SEM.
| Variable | Group | Pre | Post | Mean diff. | SEM | p-value |
|---|---|---|---|---|---|---|
| GPX | Sham | 4.06 | 4.10 | -0.045 | 0.919 | 0.963 |
| ST | 5.32 | 5.26 | 0.061 | 0.689 | 0.932 | |
| SO | 5.48 | 5.62 | -0.148 | 0.442 | 0.751 | |
| Treat | 5.55 | 3.75 | **1.79 | 0.346 | 0.004 | |
| MDA | Sham | 1.31 | 1.34 | -0.021 | 0.451 | 0.903 |
| ST | 4.20 | 4.05 | 0.147 | 0.531 | 0.792 | |
| SO | 4.41 | 4.44 | -0.029 | 0.419 | 0.946 | |
| Treat | 4.30 | 2.57 | *1.72 | 0.605 | 0.036 | |
| SOD | Sham | 6.65 | 6.82 | -0.162 | 0.650 | 0.813 |
| ST | 10.02 | 1.15 | -0.126 | 0.742 | 0.871 | |
| SO | 10.24 | 10.33 | -0.088 | 0.646 | 0.896 | |
| Treat | 10.80 | 7.55 | *3.25 | 1.06 | 0.028 |
GPx: Glutathione Proxidaze, MDA: Malondialdehyde, SOD: Superoxide dismutase, SEM: Standard error mean, SO: Sham Operated, Treat: Treatment, ST: Sham Treatment. **: P < 0.01, *: P < 0.05 between pre and post-treatment values.