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Colocalization of TRPV1 (red) and TLR4 (green) in DRG neurons. An increasing number of TRPV1-positive neurons were seen in TNBS-treated WT mice and further statistical comparisons of the percentage of TRPV1-positive neurons in different groups shown in Figure 4. Scale bar = 100 μm. WT: wild type; TLR4: Toll-like receptor 4; KO: knockout; TNBS: 2,4,6-trinitrobenzene sulfate; TRPV1: transient receptor potential vanilloid subtype 1; DAPI: 4′,6-diamidino-2-phenylindole.
