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Percentage of TRPV1-positive neurons in L5–L6 DRG of four subgroups of mice. *p < 0.05; **p < 0.01, vehicle-treated WT versus TNBS-treated WT mice; ###p < 0.001, TNBS-treated TLR4-KO versus TNBS-treated WT mice (with Bonferroni’s post hoc test). WT: wild type; TLR4: Toll-like receptor 4; KO: knockout; TNBS: 2,4,6-trinitrobenzene sulfate; TRPV1: transient receptor potential vanilloid subtype 1.
