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. 2019 Jan 29;14:583–592. doi: 10.1016/j.omtn.2019.01.009

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© 2019 The Author(s)

This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).

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Overexpression of miR-223 Promotes Cell Migration and Invasion in PC Cells

(A) Top: migration was measured by wound healing assay in PC cells after miR-223 overexpression or inhibition. Bottom: quantitative results are shown for data in the top panel. **p < 0.01 versus control. EV, empty vector; miR-223, miR-223 mimics; NC, nonspecific miRNA. (B) Left: migration and invasion assays were performed to measure the migrated capacity in PC cells after miR-223 overexpression. Right: quantitative results are shown for data in the left panel. ***p < 0.001 versus control. (C) Left: migration and invasion assays were conducted to measure the invasive capacity in PC cells after miR-223 inhibition. Right: quantitative results are shown for data in the left panel. ***p < 0.001 versus control.