Table 2. Inhibitory Activities of 6l and BIB-II in Vitro^a.

inhibitor	IN multimerization, EC50 (μM)	IN-LEDGF/p75 binding, IC50 (μM)	LEDGF/p75 independent IN activity, IC50 (μM)	LEDGF/p75 dependent IN activity, IC50 (μM)	IN-RNA binding, IC50 (μM)
6l	<1.79 ± 0.19	36.7 ± 6.2	0.48 ± 0.06	23.4 ± 0.78	0.21 ± 0.03
BIB-II	0.146 ± 0.014	0.15 ± 0.01	0.12 ± 0.04	0.15 ± 0.01	0.136 ± 0.02

^aStandard errors from two independent experiments are shown.